Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy

The human and veterinary disease complex known as African trypanosomiasis continues to inflict significant global morbidity, mortality, and economic hardship. Drug resistance and toxic side effects of old drugs call for novel and unorthodox strategies for new and safe treatment options. We designed...

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Detalles Bibliográficos
Autores principales: Rodenko, Boris, Wanner, Martin J., Alkhaldi, Abdulsalam A. M., Ebiloma, Godwin U., Barnes, Rebecca L., Kaiser, Marcel, Brun, Reto, McCulloch, Richard, Koomen, Gerrit-Jan, de Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604408/
https://www.ncbi.nlm.nih.gov/pubmed/26282430
http://dx.doi.org/10.1128/AAC.00596-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604408/
https://www.ncbi.nlm.nih.gov/pubmed/26282430
http://dx.doi.org/10.1128/AAC.00596-15

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