Molecular mechanism for preQ(1)-II riboswitch function revealed by molecular dynamics

Riboswitches are RNA molecules that regulate gene expression using conformational change, affected by binding of small molecule ligands. A crystal structure of a ligand-bound class II preQ(1) riboswitch has been determined in a previous structural study. To gain insight into the dynamics of this rib...

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Detalles Bibliográficos
Autores principales: Aytenfisu, Asaminew H., Liberman, Joseph A., Wedekind, Joseph E., Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604430/
https://www.ncbi.nlm.nih.gov/pubmed/26370581
http://dx.doi.org/10.1261/rna.051367.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604430/
https://www.ncbi.nlm.nih.gov/pubmed/26370581
http://dx.doi.org/10.1261/rna.051367.115

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