Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4

The bacterial CRISPR endoribonuclease Csy4 has recently been described as a potential RNA processing tool. Csy4 recognizes substrate RNA through a specific 28-nt hairpin sequence and cleaves at the 3′ end of the stem. To further explore applicability in mammalian cells, we introduced this hairpin at...

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Detalles Bibliográficos
Autores principales: Borchardt, Erin K., Vandoros, Leonidas A., Huang, Michael, Lackey, Patrick E., Marzluff, William F., Asokan, Aravind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604432/
https://www.ncbi.nlm.nih.gov/pubmed/26354771
http://dx.doi.org/10.1261/rna.051227.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604432/
https://www.ncbi.nlm.nih.gov/pubmed/26354771
http://dx.doi.org/10.1261/rna.051227.115

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