Cargando…

Evidence for cooperative tandem binding of hnRNP C RRMs in mRNA processing

The human hnRNP C is a ubiquitous cellular protein involved in mRNA maturation. Recently, we have shown that this protein specifically recognizes uridine (U) pentamers through its single RNA recognition motif (RRM). However, a large fraction of natural RNA targets of hnRNP C consists of much longer...

Descripción completa

Detalles Bibliográficos
Autores principales: Cieniková, Zuzana, Jayne, Sandrine, Damberger, Fred Franz, Allain, Frédéric Hai-Trieu, Maris, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604433/
https://www.ncbi.nlm.nih.gov/pubmed/26370582
http://dx.doi.org/10.1261/rna.052373.115