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Adeno-associated-virus-mediated transduction of the mammary gland enables sustained production of recombinant proteins in milk

Biopharming for the production of recombinant pharmaceutical proteins in the mammary gland of transgenic animals is an attractive but laborious alternative compared to mammalian cell fermentation. The disadvantage of the lengthy process of genetically modifying an entire animal could be circumvented...

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Detalles Bibliográficos
Autores principales: Wagner, Stefan, Thresher, Rosemary, Bland, Ross, Laible, Götz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604487/
https://www.ncbi.nlm.nih.gov/pubmed/26463440
http://dx.doi.org/10.1038/srep15115