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Intraperitoneal Administration of a Novel TAT-BDNF Peptide Ameliorates Cognitive Impairments via Modulating Multiple Pathways in Two Alzheimer’s Rodent Models

Although Alzheimer’s disease (AD) has been reported for more than 100 years, there is still a lack of effective cures for this devastating disorder. Among the various obstacles that hold back drug development, the blood-brain barrier (BBB) is one of them. Here, we constructed a novel fusion peptide...

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Detalles Bibliográficos
Autores principales: Wu, Yuanyuan, Luo, Xiaobin, Liu, Xinhua, Liu, Deyi, Wang, Xiong, Guo, Ziyuan, Zhu, Lingqiang, Tian, Qing, Yang, Xifei, Wang, Jian-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604491/
https://www.ncbi.nlm.nih.gov/pubmed/26463268
http://dx.doi.org/10.1038/srep15032