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Enhanced regeneration and functional recovery after spinal root avulsion by manipulation of the proteoglycan receptor PTPσ

Following root avulsion, spinal nerves are physically disconnected from the spinal cord. Severe motoneuron death and inefficient axon regeneration often result in devastating motor dysfunction. Newly formed axons need to extend through inhibitory scar tissue at the CNS-PNS transitional zone before e...

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Detalles Bibliográficos
Autores principales: Li, Heng, Wong, Connie, Li, Wen, Ruven, Carolin, He, Liumin, Wu, Xiaoli, Lang, Bradley T., Silver, Jerry, Wu, Wutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604492/
https://www.ncbi.nlm.nih.gov/pubmed/26464223
http://dx.doi.org/10.1038/srep14923