Molecular difference between WASP and N-WASP critical for chemotaxis of T-cells towards SDF-1α

Wiskott-Aldrich Syndrome protein (WASP) integrates cell signaling pathways to the actin cytoskeleton, which play a critical role in T-cell activation and migration. Hematopoietic cells express both WASP and neural-WASP (N-WASP) which share similar domain structure, yet WASP deficiency causes Wiskott...

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Detalles Bibliográficos
Autores principales: Jain, Neeraj, Thanabalu, Thirumaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604493/
https://www.ncbi.nlm.nih.gov/pubmed/26463123
http://dx.doi.org/10.1038/srep15031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604493/
https://www.ncbi.nlm.nih.gov/pubmed/26463123
http://dx.doi.org/10.1038/srep15031

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