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NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

BACKGROUND: Brain metastases are an increasing problem in women with invasive breast cancer. Strategies designed to treat brain metastases of breast cancer, particularly chemotherapeutics such as irinotecan, demonstrate limited efficacy. Conventional irinotecan distributes poorly to brain metastases...

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Detalles Bibliográficos
Autores principales: Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604629/
https://www.ncbi.nlm.nih.gov/pubmed/26463521
http://dx.doi.org/10.1186/s12885-015-1672-4