Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington’s disease

Mitochondrial dysfunction is implicated in multiple neurodegenerative diseases. In order to maintain a healthy population of functional mitochondria in cells, defective mitochondria must be properly eliminated by lysosomal machinery in a process referred to as mitophagy. Here, we uncover a new molec...

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Detalles Bibliográficos
Autores principales: Hwang, Sunhee, Disatnik, Marie-Hélène, Mochly-Rosen, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604685/
https://www.ncbi.nlm.nih.gov/pubmed/26268247
http://dx.doi.org/10.15252/emmm.201505256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604685/
https://www.ncbi.nlm.nih.gov/pubmed/26268247
http://dx.doi.org/10.15252/emmm.201505256

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