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VEGF dose regulates vascular stabilization through Semaphorin3A and the Neuropilin-1(+) monocyte/TGF-β1 paracrine axis
VEGF is widely investigated for therapeutic angiogenesis, but while short-term delivery is desirable for safety, it is insufficient for new vessel persistence, jeopardizing efficacy. Here, we investigated whether and how VEGF dose regulates nascent vessel stabilization, to identify novel therapeutic...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604689/ https://www.ncbi.nlm.nih.gov/pubmed/26323572 http://dx.doi.org/10.15252/emmm.201405003 |