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VEGF dose regulates vascular stabilization through Semaphorin3A and the Neuropilin-1(+) monocyte/TGF-β1 paracrine axis

VEGF is widely investigated for therapeutic angiogenesis, but while short-term delivery is desirable for safety, it is insufficient for new vessel persistence, jeopardizing efficacy. Here, we investigated whether and how VEGF dose regulates nascent vessel stabilization, to identify novel therapeutic...

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Detalles Bibliográficos
Autores principales: Groppa, Elena, Brkic, Sime, Bovo, Emmanuela, Reginato, Silvia, Sacchi, Veronica, Di Maggio, Nunzia, Muraro, Manuele G, Calabrese, Diego, Heberer, Michael, Gianni-Barrera, Roberto, Banfi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604689/
https://www.ncbi.nlm.nih.gov/pubmed/26323572
http://dx.doi.org/10.15252/emmm.201405003

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