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Altered liver expression of genes involved in lipid and glucose metabolism in mice with partial IGF-1 deficiency: an experimental approach to metabolic syndrome

BACKGROUND: Insulin growth factor 1 (IGF-1) has multiple effects on metabolism. Much evidence suggests that the deficiency of this hormone increases insulin resistance, impairs lipid metabolism, augments oxidative damage and deregulates the neuro-hormonal axis. An inverse relationship between IGF-1...

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Detalles Bibliográficos
Autores principales: De Ita, J. Rodríguez, Castilla-Cortázar, I., Aguirre, G. A., Sánchez-Yago, C., Santos-Ruiz, M. Olleros, Guerra-Menéndez, L., Martín-Estal, I., García-Magariño, M., Lara-Díaz, V. J., Puche, J. E., Muñoz, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604722/
https://www.ncbi.nlm.nih.gov/pubmed/26467524
http://dx.doi.org/10.1186/s12967-015-0684-9