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TSC-22 up-regulates collagen 3a1 gene expression in the rat heart

BACKGROUND: The transforming growth factor (TGF)-β is one of the key mediators in cardiac remodelling occurring after myocardial infarction (MI) and in hypertensive heart disease. The TGF-β-stimulated clone 22 (TSC-22) is a leucine zipper protein expressed in many tissues and possessing various tran...

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Detalles Bibliográficos
Autores principales: Kelloniemi, Annina, Aro, Jani, Näpänkangas, Juha, Koivisto, Elina, Mustonen, Erja, Ruskoaho, Heikki, Rysä, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604760/
https://www.ncbi.nlm.nih.gov/pubmed/26464165
http://dx.doi.org/10.1186/s12872-015-0121-2