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Transient, activity dependent inhibition of transmitter release from low threshold afferents mediated by GABA(A) receptors in spinal cord lamina III/IV
BACKGROUND: Presynaptic GABA(A) receptors (GABA(A)Rs) located on central terminals of low threshold afferent fibers are thought to be involved in the processing of touch and possibly in the generation of tactile allodynia in chronic pain. These GABA(A)Rs mediate primary afferent depolarization (PAD)...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605127/ https://www.ncbi.nlm.nih.gov/pubmed/26463733 http://dx.doi.org/10.1186/s12990-015-0067-5 |