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Rho/Rock signal transduction pathway is required for MSC tenogenic differentiation

Mesenchymal stem cell (MSC)-based treatments have shown promise for improving tendon healing and repair. MSCs have the potential to differentiate into multiple lineages in response to select chemical and physical stimuli, including into tenocytes. Cell elongation and cytoskeletal tension have been s...

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Detalles Bibliográficos
Autores principales: Maharam, Edward, Yaport, Miguel, Villanueva, Nathaniel L, Akinyibi, Takintope, Laudier, Damien, He, Zhiyong, Leong, Daniel J, Sun, Hui B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605238/
https://www.ncbi.nlm.nih.gov/pubmed/26509098
http://dx.doi.org/10.1038/boneres.2015.15