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Non-redundant Requirement for CXCR3 Signaling during Tumoricidal T Cell Trafficking across Tumor Vascular Checkpoints

T cell trafficking at vascular sites has emerged as a key step in antitumor immunity. Chemokines are credited with guiding the multistep recruitment of CD8(+) T cells across tumor vessels. However, the multiplicity of chemokines within tumors has obscured the contributions of individual chemokine re...

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Detalles Bibliográficos
Autores principales: Mikucki, ME, Fisher, DT, Matsuzaki, J, Skitzki, JJ, Gaulin, NB, Muhitch, JB, Ku, AW, Frelinger, JG, Odunsi, K, Gajewski, TF, Luster, AD, Evans, SS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605273/
https://www.ncbi.nlm.nih.gov/pubmed/26109379
http://dx.doi.org/10.1038/ncomms8458