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Efficient production of superior dumbbell-shaped DNA minimal vectors for small hairpin RNA expression

Genetic therapy holds great promise for the treatment of inherited or acquired genetic diseases; however, its breakthrough is hampered by the lack of suitable gene delivery systems. Dumbbell-shaped DNA minimal vectors represent an attractive, safe alternative to the commonly used viral vectors which...

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Detalles Bibliográficos
Autores principales: Yu, Han, Jiang, Xiaoou, Tan, Kar Tong, Hang, Liting, Patzel, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605290/
https://www.ncbi.nlm.nih.gov/pubmed/26068470
http://dx.doi.org/10.1093/nar/gkv583