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High-throughput prediction of RNA, DNA and protein binding regions mediated by intrinsic disorder

Intrinsically disordered proteins and regions (IDPs and IDRs) lack stable 3D structure under physiological conditions in-vitro, are common in eukaryotes, and facilitate interactions with RNA, DNA and proteins. Current methods for prediction of IDPs and IDRs do not provide insights into their functio...

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Detalles Bibliográficos
Autores principales: Peng, Zhenling, Kurgan, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605291/
https://www.ncbi.nlm.nih.gov/pubmed/26109352
http://dx.doi.org/10.1093/nar/gkv585