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High-throughput prediction of RNA, DNA and protein binding regions mediated by intrinsic disorder
Intrinsically disordered proteins and regions (IDPs and IDRs) lack stable 3D structure under physiological conditions in-vitro, are common in eukaryotes, and facilitate interactions with RNA, DNA and proteins. Current methods for prediction of IDPs and IDRs do not provide insights into their functio...
Autores principales: | Peng, Zhenling, Kurgan, Lukasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605291/ https://www.ncbi.nlm.nih.gov/pubmed/26109352 http://dx.doi.org/10.1093/nar/gkv585 |
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