hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway

The maintenance of genome stability is essential to prevent loss of genetic information and the development of diseases such as cancer. One of the most common forms of damage to the genetic code is the oxidation of DNA by reactive oxygen species (ROS), of which 8-oxo-7,8-dihydro-guanine (8-oxoG) is...

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Detalles Bibliográficos
Autores principales: Paquet, Nicolas, Adams, Mark N., Leong, Vincent, Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Beard, Sam, Burgess, Joshua T., Bolderson, Emma, O'Byrne, Ken J., Richard, Derek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605301/
https://www.ncbi.nlm.nih.gov/pubmed/26261212
http://dx.doi.org/10.1093/nar/gkv790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605301/
https://www.ncbi.nlm.nih.gov/pubmed/26261212
http://dx.doi.org/10.1093/nar/gkv790

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