NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins

The Sm proteins are loaded on snRNAs by the SMN complex, but how snRNP-specific proteins are assembled remains poorly characterized. U4 snRNP and box C/D snoRNPs have structural similarities. They both contain the 15.5K and proteins with NOP domains (PRP31 for U4, NOP56/58 for snoRNPs). Biogenesis o...

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Detalles Bibliográficos
Autores principales: Bizarro, Jonathan, Dodré, Maxime, Huttin, Alexandra, Charpentier, Bruno, Schlotter, Florence, Branlant, Christiane, Verheggen, Céline, Massenet, Séverine, Bertrand, Edouard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605303/
https://www.ncbi.nlm.nih.gov/pubmed/26275778
http://dx.doi.org/10.1093/nar/gkv809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605303/
https://www.ncbi.nlm.nih.gov/pubmed/26275778
http://dx.doi.org/10.1093/nar/gkv809

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