Structure of mitochondrial poly(A) RNA polymerase reveals the structural basis for dimerization, ATP selectivity and the SPAX4 disease phenotype

Polyadenylation, performed by poly(A) polymerases (PAPs), is a ubiquitous post-transcriptional modification that plays key roles in multiple aspects of RNA metabolism. Although cytoplasmic and nuclear PAPs have been studied extensively, the mechanism by which mitochondrial PAP (mtPAP) selects adenos...

Descripción completa

Detalles Bibliográficos
Autores principales: Lapkouski, Mikalai, Hällberg, B. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605311/
https://www.ncbi.nlm.nih.gov/pubmed/26319014
http://dx.doi.org/10.1093/nar/gkv861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605311/
https://www.ncbi.nlm.nih.gov/pubmed/26319014
http://dx.doi.org/10.1093/nar/gkv861

Ejemplares similares