Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription

Folding of the LTR promoter into dynamic G-quadruplex conformations has been shown to suppress its transcriptional activity in HIV-1. Here we sought to identify the proteins that control the folding of this region of proviral genome by inducing/stabilizing G-quadruplex structures. The implementation...

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Detalles Bibliográficos
Autores principales: Tosoni, Elena, Frasson, Ilaria, Scalabrin, Matteo, Perrone, Rosalba, Butovskaya, Elena, Nadai, Matteo, Palù, Giorgio, Fabris, Dan, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605322/
https://www.ncbi.nlm.nih.gov/pubmed/26354862
http://dx.doi.org/10.1093/nar/gkv897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605322/
https://www.ncbi.nlm.nih.gov/pubmed/26354862
http://dx.doi.org/10.1093/nar/gkv897

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