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A Homogenous Bioluminescent System for Measuring GTPase, GTPase Activating Protein, and Guanine Nucleotide Exchange Factor Activities

GTPases play a major role in various cellular functions such as cell signaling, cell proliferation, cell differentiation, cytoskeleton modulation, and cell motility. Deregulation or mutation of these proteins has considerable consequences resulting in multiple pathological conditions. Targeting GTPa...

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Detalles Bibliográficos
Autores principales: Mondal, Subhanjan, Hsiao, Kevin, Goueli, Said A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605356/
https://www.ncbi.nlm.nih.gov/pubmed/26167953
http://dx.doi.org/10.1089/adt.2015.643