Cargando…
The frequency of BRCA1 founder mutation c.5266dupC (5382insC) in breast cancer patients from Ukraine
Germ-line mutations in several genes, such as BRCA1 and BRCA2, are known to increase the risk of breast cancer. These heritable mutations are unequally represented among populations with different ethnic background due to founder effects and thereby contribute to differences in breast cancer rates i...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605451/ https://www.ncbi.nlm.nih.gov/pubmed/26468334 http://dx.doi.org/10.1186/s13053-015-0040-3 |