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The frequency of BRCA1 founder mutation c.5266dupC (5382insC) in breast cancer patients from Ukraine

Germ-line mutations in several genes, such as BRCA1 and BRCA2, are known to increase the risk of breast cancer. These heritable mutations are unequally represented among populations with different ethnic background due to founder effects and thereby contribute to differences in breast cancer rates i...

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Detalles Bibliográficos
Autores principales: Gorodetska, Ielizaveta, Serga, Svitlana, Levkovich, Natalia, Lahuta, Tetiana, Ostapchenko, Ludmila, Demydov, Serhyi, Anikusko, Nikolay, Cheshuk, Valeriy, Smolanka, Ivan, Sklyar, Svitlana, Polenkov, Serhyi, Boichenko, Oleksander, Kozeretska, Iryna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605451/
https://www.ncbi.nlm.nih.gov/pubmed/26468334
http://dx.doi.org/10.1186/s13053-015-0040-3