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Transmissibility of H-Type Bovine Spongiform Encephalopathy to Hamster PrP Transgenic Mice

Two distinct forms of atypical bovine spongiform encephalopathies (H-BSE and L-BSE) can be distinguished from classical (C-) BSE found in cattle based on biochemical signatures of disease-associated prion protein (PrP(Sc)). H-BSE is transmissible to wild-type mice—with infected mice showing a long s...

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Detalles Bibliográficos
Autores principales: Okada, Hiroyuki, Masujin, Kentaro, Miyazawa, Kohtaro, Yokoyama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605493/
https://www.ncbi.nlm.nih.gov/pubmed/26466381
http://dx.doi.org/10.1371/journal.pone.0138977