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Comparing the Primary and Recall Immune Response Induced by a New EV71 Vaccine Using Systems Biology Approaches

Three inactivated EV71 whole-virus vaccines have completed Phase III clinical trials in mainland China, with high efficacy, satisfactory safety, and sustained immunogenicity. However, the molecular mechanisms how this new vaccine elicit potent immune response remain poorly understood. To characteriz...

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Detalles Bibliográficos
Autores principales: Shao, Jie, Zhang, Junnan, Wu, Xing, Mao, Qunying, Chen, Pan, Zhu, Fengcai, Xu, Miao, Kong, Wei, Liang, Zhenglun, Wang, Junzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605509/
https://www.ncbi.nlm.nih.gov/pubmed/26465882
http://dx.doi.org/10.1371/journal.pone.0140515