Cargando…

Comparing the Primary and Recall Immune Response Induced by a New EV71 Vaccine Using Systems Biology Approaches

Three inactivated EV71 whole-virus vaccines have completed Phase III clinical trials in mainland China, with high efficacy, satisfactory safety, and sustained immunogenicity. However, the molecular mechanisms how this new vaccine elicit potent immune response remain poorly understood. To characteriz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Jie, Zhang, Junnan, Wu, Xing, Mao, Qunying, Chen, Pan, Zhu, Fengcai, Xu, Miao, Kong, Wei, Liang, Zhenglun, Wang, Junzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605509/ https://www.ncbi.nlm.nih.gov/pubmed/26465882 http://dx.doi.org/10.1371/journal.pone.0140515

Ejemplares similares

EV71 vaccine, an invaluable gift for children
por: Liang, Zhenglun, et al.
Publicado: (2014)

Comparative Analysis of the Immunogenicity and Protective Effects of Inactivated EV71 Vaccines in Mice
por: Mao, Qunying, et al.
Publicado: (2012)

EV-A71 vaccine licensure: a first step for multivalent enterovirus vaccine to control HFMD and other severe diseases
por: Mao, Qunying, et al.
Publicado: (2016)

Cross-Antigenicity between EV71 Sub-Genotypes: Implications for Vaccine Efficacy
por: Liu, Pei, et al.
Publicado: (2021)

The Cross-Neutralizing Activity of Enterovirus 71 Subgenotype C4 Vaccines in Healthy Chinese Infants and Children
por: Mao, Qunying, et al.
Publicado: (2013)

Study of the Integrated Immune Response Induced by an Inactivated EV71 Vaccine
por: Liu, Longding, et al.
Publicado: (2013)

Development and Evaluation of a Pseudovirus-Luciferase Assay for Rapid and Quantitative Detection of Neutralizing Antibodies against Enterovirus 71
por: Wu, Xing, et al.
Publicado: (2013)

A cross-sectional seroepidemiology study of EV-D68 in China
por: Sun, Shiyang, et al.
Publicado: (2018)

Analysis of Cross-Reactive Neutralizing Antibodies in Human HFMD Serum with an EV71 Pseudovirus-Based Assay
por: Zhang, Huafei, et al.
Publicado: (2014)

Production of EV71 vaccine candidates
por: Chong, Pele, et al.
Publicado: (2012)

Progress on the research and development of inactivated EV71 whole-virus vaccines
por: Liang, Zheng-Lun, et al.
Publicado: (2013)

Protective effect of enterovirus-71 (EV71) virus-like particle vaccine against lethal EV71 infection in a neonatal mouse model
por: CAO, LEI, et al.
Publicado: (2015)

Induction of SOCS Expression by EV71 Infection Promotes EV71 Replication
por: Gao, Wenying, et al.
Publicado: (2020)

Regulatory science accelerates the development of biotechnology drugs and vaccines by NIFDC
por: Liang, Zhenglun, et al.
Publicado: (2014)

Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71
por: Dang, Minghao, et al.
Publicado: (2014)

COVID-19 Vaccines: Current Understanding on Immunogenicity, Safety, and Further Considerations
por: He, Qian, et al.
Publicado: (2021)

Short-Fragment DNA Residue from Vaccine Purification Processes Promotes Immune Response to the New Inactivated EV71 Vaccine by Upregulating TLR9 mRNA
por: Shao, Jie, et al.
Publicado: (2016)

Plant-Produced Anti-Enterovirus 71 (EV71) Monoclonal Antibody Efficiently Protects Mice Against EV71 Infection
por: Rattanapisit, Kaewta, et al.
Publicado: (2019)

EV71 vaccines: a milestone in the history of global vaccine development
por: Lu, Shan
Publicado: (2014)

Immunological Evaluation and Comparison of Different EV71 Vaccine Candidates
por: Chou, Ai-Hsiang, et al.
Publicado: (2012)

COVID-19 vaccines: progress and understanding on quality control and evaluation
por: Mao, Qunying, et al.
Publicado: (2021)

Inhibition of Enterovirus 71 (EV-71) Infections by a Novel Antiviral Peptide Derived from EV-71 Capsid Protein VP1
por: Tan, Chee Wah, et al.
Publicado: (2012)

Recent Progress towards Novel EV71 Anti-Therapeutics and Vaccines
por: Ng, Qingyong, et al.
Publicado: (2015)

Flavonoids as Antiviral Agents for Enterovirus A71 (EV-A71)
por: Lalani, Salima, et al.
Publicado: (2020)

A rapid and quantitative assay for measuring neutralizing antibodies of Coxsackievirus B3
por: Chen, Pan, et al.
Publicado: (2016)

Heterologous prime-boost: breaking the protective immune response bottleneck of COVID-19 vaccine candidates
por: He, Qian, et al.
Publicado: (2021)

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71
por: Wang, Xiangxi, et al.
Publicado: (2012)

A comparison of the test-negative and the matched case-control study designs for estimation of EV71 vaccine immunological surrogate endpoints from a randomized controlled trial
por: Zhang, Li, et al.
Publicado: (2022)

Human SCARB2-Mediated Entry and Endocytosis of EV71
por: Lin, Yi-Wen, et al.
Publicado: (2012)

Phenotypic and Genotypic Characteristics of Novel Mouse Cell Line (NIH/3T3)-Adapted Human Enterovirus 71 Strains (EV71:TLLm and EV71:TLLmv)
por: Victorio, Carla Bianca Luena, et al.
Publicado: (2014)

Delivery of Human EV71 Receptors by Adeno-Associated Virus Increases EV71 Infection-Induced Local Inflammation in Adult Mice
por: Hsiao, Hung-Bo, et al.
Publicado: (2014)

The mature EV71 virion induced a broadly cross-neutralizing VP1 antibody against subtypes of the EV71 virus
por: Wu, Chia-Ying, et al.
Publicado: (2019)

EV71 virus-like particles produced by co-expression of capsid proteins in yeast cells elicit humoral protective response against EV71 lethal challenge
por: Wang, Xiaowen, et al.
Publicado: (2016)

Correction: Phenotypic and Genotypic Characteristics of Novel Mouse Cell Line (NIH/3T3)-Adapted Human Enterovirus 71 Strains (EV71:TLLm and EV71:TLLmv)
Publicado: (2014)

Inhibition of EV71 by curcumin in intestinal epithelial cells
por: Huang, Hsing-I, et al.
Publicado: (2018)

Establishment of the 1st Chinese national standard for CA6 neutralizing antibody
por: Wang, Yiping, et al.
Publicado: (2023)

Insights into innate and adaptive immune responses in vaccine development against EV-A71
por: Lim, Hui Xuan, et al.
Publicado: (2019)

Research Advances on the Stability of mRNA Vaccines
por: Cheng, Feiran, et al.
Publicado: (2023)

Monoclonal antibody induced with inactived EV71-Hn2 virus protects mice against lethal EV71-Hn2 virus infection
por: Chang, Guo-hui, et al.
Publicado: (2010)

The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection—suramin inhibits EV71 infection in vitro and in vivo
por: Ren, Peijun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8ond5qrfdk1ug5uqu9q68jd5fb