A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells

Rpn13 is a proteasome ubiquitin receptor that has emerged as a therapeutic target for human cancers. Its ubiquitin-binding activity is confined to an N-terminal Pru (pleckstrin-like receptor for ubiquitin) domain that also docks it into the proteasome, while its C-terminal DEUBAD (DEUBiquitinase ADa...

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Detalles Bibliográficos
Autores principales: Lu, Xiuxiu, Liu, Fen, Durham, Sarah E., Tarasov, Sergey G., Walters, Kylie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605517/
https://www.ncbi.nlm.nih.gov/pubmed/26466095
http://dx.doi.org/10.1371/journal.pone.0140518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605517/
https://www.ncbi.nlm.nih.gov/pubmed/26466095
http://dx.doi.org/10.1371/journal.pone.0140518

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