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VHL Genetic Alteration in CCRCC Does Not Determine De-Regulation of HIF, CAIX, hnRNP A2/B1 and Osteopontin

Background: von Hippel–Lindau (VHL) tumour suppressor gene inactivation is associated with clear cell renal cell carcinoma (CCRCC) development. The VHL protein (pVHL) has been proposed to regulate the expression of several proteins including Hypoxia Inducible Factor-α (HIF-α), carbonic anhydrase (CA...

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Detalles Bibliográficos
Autores principales: Nyhan, Michelle J., El Mashad, Shereen M., O’Donovan, Tracey R., Ahmad, Sarfraz, Collins, Chris, Sweeney, Paul, Rogers, Eamonn, O’Sullivan, Gerald C., McKenna, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605534/
https://www.ncbi.nlm.nih.gov/pubmed/20978319
http://dx.doi.org/10.3233/ACP-CLO-2010-0541