Strategies for H-score Normalization of Preanalytical Technical Variables with Potential Utility to Immunohistochemical-Based Biomarker Quantitation in Therapeutic Reponse Diagnostics

Digital quantitative immunohistochemical analysis of protein biomarker expression offers a broad dynamic range against which clinical outcomes may be measured. Semi-quantitative expression data represented as an H-score is produced by computer generated average intensity of positive staining given w...

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Detalles Bibliográficos
Autores principales: Pierceall, William E., Wolfe, Michele, Suschak, Jessica, Chang, Hua, Chen, Yan, Sprott, Kam M., Kutok, Jeffery L., Quan, Stella, Weaver, David T., Ward, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2011
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605628/
https://www.ncbi.nlm.nih.gov/pubmed/21677381
http://dx.doi.org/10.3233/ACP-2011-014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605628/
https://www.ncbi.nlm.nih.gov/pubmed/21677381
http://dx.doi.org/10.3233/ACP-2011-014

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