A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef

The HIV-1-encoded protein, Nef, plays a key role in the development of AIDS. One of Nef’s functions is to keep MHC class I off the surface of infected cells, a process that requires the host proteins clathrin and AP-1. To identify other proteins involved in this pathway, we carried out a genome-wide...

Descripción completa

Detalles Bibliográficos
Autores principales: Choma, Maja K., Lumb, Jennifer, Kozik, Patrycja, Robinson, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605695/
https://www.ncbi.nlm.nih.gov/pubmed/26466362
http://dx.doi.org/10.1371/journal.pone.0140404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605695/
https://www.ncbi.nlm.nih.gov/pubmed/26466362
http://dx.doi.org/10.1371/journal.pone.0140404

Ejemplares similares