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Red Blood Cells Preconditioned with Hemin Are Less Permissive to Plasmodium Invasion In Vivo and In Vitro

Malaria is a parasitic disease that causes severe hemolytic anemia in Plasmodium-infected hosts, which results in the release and accumulation of oxidized heme (hemin). Although hemin impairs the establishment of Plasmodium immunity in vitro and in vivo, mice preconditioned with hemin develop lower...

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Detalles Bibliográficos
Autores principales: Gaudreault, Véronique, Wirbel, Jakob, Jardim, Armando, Rohrbach, Petra, Scorza, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605744/
https://www.ncbi.nlm.nih.gov/pubmed/26465787
http://dx.doi.org/10.1371/journal.pone.0140805