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KCC2 expression supersedes NKCC1 in mature fiber cells in mouse and rabbit lenses

PURPOSE: Na-K-Cl cotransporter 1 (NKCC1) and K-Cl cotransporter 2 (KCC2) have fundamental roles in neuron differentiation that are integrated with gamma-aminobutyric acid (GABA) and glutamate receptors, GABA synthesized by GAD25/65/67 encoded by GAD1/GAD2 genes, and GABA transporters (GATs). Cells i...

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Detalles Bibliográficos
Autores principales: Frederikse, Peter H., Kasinathan, Chinnaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605749/
https://www.ncbi.nlm.nih.gov/pubmed/26539026