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Localization of ORC1 During the Cell Cycle in Human Leukemia Cells

The interaction of the origin recognition complex (ORC) with replication origins is a critical parameter in eukaryotic replication initiation. In mammals the ORC remains bound except during mitosis, thus the localization of ORC complexes allows localization of origins. A monoclonal antibody that rec...

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Detalles Bibliográficos
Autores principales: Coffman, Frederick D., Reyes, Mai-Ling, Brown, Monique, Lambert, W. Clark, Cohen, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605756/
https://www.ncbi.nlm.nih.gov/pubmed/22045277
http://dx.doi.org/10.3233/ACP-2011-0041