Activating Mutation (V617F) in the Tyrosine Kinase JAK2 is Absent in Locally-Confined or Castration-Resistant Prostate Cancer

Background: Transcription factor Stat5a/b is highly critical for the viability of human prostate cancer cells in vitro and for prostate tumor growth in vivo. Stat5 is constitutively active in clinical prostate cancers but not in the normal human prostate epithelium. Moreover, Stat5a/b activation in...

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Detalles Bibliográficos
Autores principales: Gu, Lei, Zhu, Xian-Hua, Visakorpi, Tapio, Alanen, Kalle, Mirtti, Tuomas, Edmonston, Tina Bocker, Nevalainen, Marja T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605774/
https://www.ncbi.nlm.nih.gov/pubmed/20966544
http://dx.doi.org/10.3233/ACP-CLO-2010-0534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605774/
https://www.ncbi.nlm.nih.gov/pubmed/20966544
http://dx.doi.org/10.3233/ACP-CLO-2010-0534

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