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TGFβ-signaling in Squamous Cell Carcinoma Occurring in Recessive Dystrophic Epidermolysis Bullosa

Background: Recessive dystrophic epidermolysis bullosa (RDEB) is a hereditary skin disorder characterized by mechanical fragility of the skin, resulting in blistering and chronic wounds. The causative mutations lie in the COL7A1 gene. Patients suffering from RDEB have a high risk to develop aggressi...

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Detalles Bibliográficos
Autores principales: Knaup, Julia, Gruber, Christina, Krammer, Barbara, Ziegler, Verena, Bauer, Johann, Verwanger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605790/
https://www.ncbi.nlm.nih.gov/pubmed/22002724
http://dx.doi.org/10.3233/ACP-2011-0039