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Synthesis and oral hypoglycemic effect of novel thiazine containing trisubstituted benzenesulfonylurea derivatives

A new series of 3-(4-substituted phenyl)-1-(4-(4,6-dimethyl-6H-1,3-thiazin-2-yl)phenylsulfonyl)-1-substituted urea (5a–o) was synthesized by an effectual route via sulfonylcarbamates and explores the novel site for substitution in sulfonylurea as well as the way of thiazine can be prepared. The mole...

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Detalles Bibliográficos
Autores principales: Thakur, Alok Singh, Deshmukh, Ravitas, Jha, Arvind Kumar, Sudhir Kumar, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605906/
https://www.ncbi.nlm.nih.gov/pubmed/26594112
http://dx.doi.org/10.1016/j.jsps.2014.11.017