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LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes

Human African trypanosomiasis is a neglected tropical disease caused by the protozoan parasite, Trypanosoma brucei. In the mammalian bloodstream, the trypanosome’s metabolism differs significantly from that of its host. For example, the parasite relies exclusively on glycolysis for energy source. Re...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Hyun, Achcar, Fiona, Breitling, Rainer, Burgess, Karl E., Barrett, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605981/
https://www.ncbi.nlm.nih.gov/pubmed/26491423
http://dx.doi.org/10.1007/s11306-015-0827-2