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Disuse rescues the age-impaired adaptive response to external loading in mice

SUMMARY: We aimed to determine whether aged bone’s diminished response to mechanical loading could be rescued by modulating habitual activity. By reducing background loading, aged bone’s response to loading increased to a level no different to young mice. This suggests, given the right stimulus, tha...

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Detalles Bibliográficos
Autores principales: Meakin, L. B., Delisser, P. J., Galea, G. L., Lanyon, L. E., Price, J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605986/
https://www.ncbi.nlm.nih.gov/pubmed/25920749
http://dx.doi.org/10.1007/s00198-015-3142-x