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Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding

BACKGROUND: A procoagulant state is implicated in cerebral malaria (CM) pathogenesis, but whether disseminated intravascular coagulation (DIC) is present or associated with a fatal outcome is unclear. OBJECTIVES: To determine the frequency of overt DIC, according to ISTH criteria, in children with f...

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Detalles Bibliográficos
Autores principales: Moxon, C. A., Chisala, N. V., Mzikamanda, R., MacCormick, I., Harding, S., Downey, C., Molyneux, M., Seydel, K. B., Taylor, T. E., Heyderman, R. S., Toh, C.‐H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605993/
https://www.ncbi.nlm.nih.gov/pubmed/26186686
http://dx.doi.org/10.1111/jth.13060