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The Potential Role of NFAT5 and Osmolarity in Peritoneal Injury

A rise in osmotic concentration (osmolarity) activates the transcription factor Nuclear Factor of Activated T Cells 5 (NFAT5, also known as Tonicity-responsive Enhancer Binding Protein, TonEBP). This is part of a regulatory mechanism of cells adjusting to environments of high osmolarity. Under physi...

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Detalles Bibliográficos
Autores principales: Seeger, Harald, Kitterer, Daniel, Latus, Joerg, Alscher, Mark Dominik, Braun, Niko, Segerer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606082/
https://www.ncbi.nlm.nih.gov/pubmed/26495302
http://dx.doi.org/10.1155/2015/578453