Cognitive Deficits, Changes in Synaptic Function, and Brain Pathology in a Mouse Model of Normal Aging

Age is the main risk factor for sporadic Alzheimer’s disease. Yet, cognitive decline in aged rodents has been less well studied, possibly due to concomitant changes in sensory or locomotor function that can complicate cognitive tests. We tested mice that were 3, 11, and 23 months old in cognitive, s...

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Detalles Bibliográficos
Autores principales: Weber, Martin, Wu, Tiffany, Hanson, Jesse E., Alam, Nazia M., Solanoy, Hilda, Ngu, Hai, Lauffer, Benjamin E., Lin, Han H., Dominguez, Sara L., Reeder, Jens, Tom, Jennifer, Steiner, Pascal, Foreman, Oded, Prusky, Glen T., Scearce-Levie, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2015
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606159/
https://www.ncbi.nlm.nih.gov/pubmed/26473169
http://dx.doi.org/10.1523/ENEURO.0047-15.2015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606159/
https://www.ncbi.nlm.nih.gov/pubmed/26473169
http://dx.doi.org/10.1523/ENEURO.0047-15.2015

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