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Cognitive Deficits, Changes in Synaptic Function, and Brain Pathology in a Mouse Model of Normal Aging
Age is the main risk factor for sporadic Alzheimer’s disease. Yet, cognitive decline in aged rodents has been less well studied, possibly due to concomitant changes in sensory or locomotor function that can complicate cognitive tests. We tested mice that were 3, 11, and 23 months old in cognitive, s...
Autores principales: | Weber, Martin, Wu, Tiffany, Hanson, Jesse E., Alam, Nazia M., Solanoy, Hilda, Ngu, Hai, Lauffer, Benjamin E., Lin, Han H., Dominguez, Sara L., Reeder, Jens, Tom, Jennifer, Steiner, Pascal, Foreman, Oded, Prusky, Glen T., Scearce-Levie, Kimberly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606159/ https://www.ncbi.nlm.nih.gov/pubmed/26473169 http://dx.doi.org/10.1523/ENEURO.0047-15.2015 |
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