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Genetic Variants of C-5312T REN Increased Renin Levels and Diastolic Blood Pressure Response to Angiotensin Receptor Blockers

Renin catalyzes the cleavage of angiotensinogen into angiotensin I. Genetic variant C-5312T of renin enhancer has been reported to increase in vitro renin gene transcription. However, no obvious in vivo study was performed to see the renin level in C-5312T when treated with angiotensin receptor bloc...

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Detalles Bibliográficos
Autores principales: Rohman, Mohammad Saifur, Dewi Satiti, Ika Arum, Widodo, Nashi, Lukitasari, Mifetika, Sujuti, Hidayat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606213/
https://www.ncbi.nlm.nih.gov/pubmed/26495141
http://dx.doi.org/10.1155/2015/930631