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Systematic Analysis of the Associations between Adverse Drug Reactions and Pathways
Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic dat...
Autores principales: | Chen, Xiaowen, Wang, Yanqiu, Wang, Pingping, Lian, Baofeng, Li, Chunquan, Wang, Jing, Li, Xia, Jiang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606217/ https://www.ncbi.nlm.nih.gov/pubmed/26495310 http://dx.doi.org/10.1155/2015/670949 |
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