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Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish

Pharmacological studies in mammals suggest that norepinephrine (NE) plays an important role in promoting arousal. However, the role of endogenous NE is unclear, with contradicting reports concerning the sleep phenotypes of mice lacking NE due to mutation of dopamine β-hydroxylase (dbh). To investiga...

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Detalles Bibliográficos
Autores principales: Singh, Chanpreet, Oikonomou, Grigorios, Prober, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606453/
https://www.ncbi.nlm.nih.gov/pubmed/26374985
http://dx.doi.org/10.7554/eLife.07000