Loss of DNA methylation at imprinted loci is a frequent event in hepatocellular carcinoma and identifies patients with shortened survival

BACKGROUND: Aberrant DNA methylation at imprinted loci is an important molecular mechanism contributing to several developmental and pathological disorders including cancer. However, knowledge about imprinting defects due to DNA methylation changes is relatively limited in hepatocellular carcinoma (...

Descripción completa

Detalles Bibliográficos
Autores principales: Anwar, Sumadi Lukman, Krech, Till, Hasemeier, Britta, Schipper, Elisa, Schweitzer, Nora, Vogel, Arndt, Kreipe, Hans, Lehmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606497/
https://www.ncbi.nlm.nih.gov/pubmed/26473022
http://dx.doi.org/10.1186/s13148-015-0145-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606497/
https://www.ncbi.nlm.nih.gov/pubmed/26473022
http://dx.doi.org/10.1186/s13148-015-0145-6

Ejemplares similares